Enhance MD vs Willow: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Enhance MD and Willow to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 6.9). That said, Willow may be the better fit if you are looking for users who want a balance of quality care and reasonable pricing.
Enhance MD scores 8.3/10 in our independent evaluation at $249/month, while Willow scores 6.9/10 at $160/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Enhance MD | Willow |
|---|---|---|
| Monthly Price | $249 | $160 |
| Rating | 8.3 / 10 | 6.9 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified physicians | Licensed physicians, ongoing check-ins |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Enhance MD: Detailed Look
Enhance MD
Physician-led weight management with NAD+ options
Pros
- Affordable entry point starting at $115/month
- Unique NAD+ therapy option alongside GLP-1
- Board-certified physicians lead all protocols
Cons
- NAD+ weight loss claims lack strong clinical evidence
- Less transparent about which medications are compounded vs brand
Budget-conscious users interested in combination therapies
Willow: Detailed Look
Willow
Personalized GLP-1 weight loss with ongoing clinical support
Pros
- Personalized treatment plans tailored to your health profile
- Licensed physicians in all 50 states
- Both brand-name and compounded options available
- Free shipping with cancel-anytime flexibility
Cons
- Higher starting price than some compounded-only options
- Newer platform — fewer long-term patient reviews available
Users who want a balance of quality care and reasonable pricing
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Willow at $160/month. Starting price, varies by medication.
Enhance MD has the edge with a 8.3 rating.
Compare their support: Enhance MD offers board-certified physicians, while Willow provides licensed physicians, ongoing check-ins.
Enhance MD at $249/month may offer features that justify the premium.
Frequently Asked Questions
Is Enhance MD better than Willow?
Enhance MD has a 8.3 rating while Willow has a 6.9 rating. The better choice depends on your priorities — Enhance MD is best for budget-conscious users interested in combination therapies, while Willow is best for users who want a balance of quality care and reasonable pricing.
How much does Enhance MD cost compared to Willow?
Enhance MD starts at $249/month (semaglutide $249/mo; tirzepatide $379/mo; annual plans save ~15%), while Willow starts at $160/month (starting price, varies by medication).
Do Enhance MD and Willow accept insurance?
Enhance MD does not accept insurance. Willow does not accept insurance.
Which GLP-1 medications does Enhance MD offer vs Willow?
Enhance MD offers Semaglutide, Tirzepatide, NAD+. Willow offers Semaglutide, Tirzepatide.
Can I cancel Enhance MD or Willow at any time?
Enhance MD allows cancel anytime. Willow also allows cancel anytime.
Are Enhance MD and Willow available in my state?
Enhance MD is available in all 50 states. Willow is available in all 50 states.
Not sure Enhance MD or Willow is right for you?
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