Yucca Health vs ShedRx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Yucca Health and ShedRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Yucca Health
Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.2 vs 8.8), more affordable pricing. That said, ShedRx may be the better fit if you are looking for users who want multiple medication delivery forms and a money-back weight loss guarantee.
Yucca Health scores 9.2/10 in our independent evaluation at $146/month, while ShedRx scores 8.8/10 at $199/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Yucca Health | ShedRx |
|---|---|---|
| Monthly Price | $146 | $199 |
| Rating | 9.2 / 10 | 8.8 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | No | Yes |
| Medical Support | Licensed U.S. physicians (Dr. Wasef, Dr. Sakla), provider-guided care, 24hr review | Licensed physicians, health coaching, supplement guidance |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Yucca Health: Detailed Look
Yucca Health
LegitScript-certified GLP-1 provider with named physicians and BNPL financing
Pros
- LegitScript certified — pharmacy and telehealth verified
- 4.6/5 Trustpilot rating from 1,000+ verified patient reviews
- Named physicians: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
- Buy now, pay later via Klarna, Affirm, and Afterpay
Cons
- Best pricing requires 6-month commitment
- Compounded medications only — no brand-name options
Users who want a LegitScript-certified provider with verified patient reviews and flexible financing
ShedRx: Detailed Look
ShedRx
150K+ members with 5 medication forms — injections, oral drops, lozenges, tablets, and pills
Pros
- Most delivery forms of any provider: injections, oral drops, lozenges, tablets, and pills
- 10% weight loss guarantee within 9 months or full refund
- Both compounded and brand-name options (Wegovy, Zepbound)
- 150,000+ members, health coaching and supplements included
Cons
- Price increases at higher doses (up to $299/mo)
- Mixed customer service reviews — communication speed can lag
Users who want multiple medication delivery forms and a money-back weight loss guarantee
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Yucca Health at $146/month. $146/mo month-to-month semaglutide, or $125/mo on the 6-month plan ($750 total); tirzepatide from $225/mo. Klarna/Affirm/Afterpay available..
Yucca Health has the edge with a 9.2 rating.
Yucca Health focuses on compounded medications at a lower price point.
Compare their support: Yucca Health offers licensed u.s. physicians (dr. wasef, dr. sakla), provider-guided care, 24hr review, while ShedRx provides licensed physicians, health coaching, supplement guidance.
ShedRx at $199/month may offer features that justify the premium.
Frequently Asked Questions
Is Yucca Health better than ShedRx?
Yucca Health has a 9.2 rating while ShedRx has a 8.8 rating. The better choice depends on your priorities — Yucca Health is best for users who want a legitscript-certified provider with verified patient reviews and flexible financing, while ShedRx is best for users who want multiple medication delivery forms and a money-back weight loss guarantee.
How much does Yucca Health cost compared to ShedRx?
Yucca Health starts at $146/month ($146/mo month-to-month semaglutide, or $125/mo on the 6-month plan ($750 total); tirzepatide from $225/mo. klarna/affirm/afterpay available.), while ShedRx starts at $199/month ($199/mo semaglutide starting dose, up to $299/mo at higher doses. brand pathway $99/mo + pharmacy cost.).
Do Yucca Health and ShedRx accept insurance?
Yucca Health does not accept insurance. ShedRx does not accept insurance.
Which GLP-1 medications does Yucca Health offer vs ShedRx?
Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+. ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound.
Can I cancel Yucca Health or ShedRx at any time?
Yucca Health may have cancellation restrictions. ShedRx also allows cancel anytime.
Are Yucca Health and ShedRx available in my state?
Yucca Health is available in all 50 states. ShedRx is available in all 50 states.
Not sure Yucca Health or ShedRx is right for you?
Answer 6 questions and we'll match you with the best program for your budget and goals.