Independent review · Last updated May 2026

Enhance MD Review

Physician-led weight management with NAD+ options

8.3

Good

Monthly cost

$249

Semaglutide $249/mo; tirzepatide $379/mo; annual plans save ~15%

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Pros

Affordable entry point starting at $115/month
Unique NAD+ therapy option alongside GLP-1
Board-certified physicians lead all protocols

Cons

NAD+ weight loss claims lack strong clinical evidence
Less transparent about which medications are compounded vs brand

Enhance MD at a glance

Best for: Budget-conscious users interested in combination therapies
Medications: Semaglutide, Tirzepatide, NAD+
FDA-approved: Yes (brand-name available)
Type: Brand & compounded
Insurance: Self-pay
Oral option: Injection only
Coverage: All 50 states
Free shipping: Yes
Cancel anytime: Yes
Consultation fee: Included
Medical support: Board-certified physicians

Our verdict

Enhance MD is best for budget-conscious users interested in combination therapies.

We rate it 8.3/10 (Good) based on our 5-criteria methodology. Sign up via the button below if it’s the right fit.

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